Dry material is the stable form
Water participates in most of the reactions that degrade peptides. Removing it by freeze-drying slows hydrolysis, deamidation and several other routes to the point where a well-dried peptide stored cold and dark has a usable life measured in years rather than weeks.
This is why material ships as a dry solid. A short period at ambient temperature during transit is a normal and expected part of the process for lyophilized material.
Reconstitution changes the arithmetic
Once a peptide is in solution the protective effect of dryness is gone, and stability is then governed by temperature, pH, the solvent used and how many times the vial is opened. Solutions are handled cold and used within a much shorter window than the dry material they came from.
Practical handling
- Move material to its documented storage condition on arrival rather than leaving it at ambient temperature
- Keep vials dark; several peptide side chains are photosensitive
- Avoid repeated freeze-thaw cycling, which is more damaging than continuous storage at a single temperature
- Allow a cold vial to reach room temperature before opening, so that atmospheric moisture does not condense onto the cold solid
Research use only. This page is explanatory and does not recommend any use, quantity or procedure. REVIVE LAB supplies reference materials for laboratory research. These are not medicines and are not for human or veterinary consumption. Anyone considering the use of any compound in humans should do so only under qualified medical supervision.